High Hopes for New Comprehensive Treatments in Schizophrenia

CALPACS members and the general community are cordially invited to our Fall Luncheon. This year, we will be treated with a lecture from Kristen Gilliland, Ph.D., from Vanderbilt University. Dr. Gilliland will detail the underlying mechanisms of schizophrenia and the new research into possible novel therapies. The event will include appetizers and a three course lunch. Attendees can also choose to stay for the annual open session of the CALPACS Executive Committee.

This event has reached capacity. Please click “contact us” above to use our contact form to get on our waiting list in case of any cancellations. We look forward to seeing you.

CALPACS members are cordially invited to our Fall Luncheon. This year, we will be treated to an inside look at the development of small molecule therapeutics by Vu Ma, a decades-long member of Amgen’s research arm in Thousand Oaks, CA. The event will include appetizers and a three course lunch. Attendees can also choose to stay for the annual open session of the CALPACS Executive Committee.

Speaker: Vu Ma, Senior Scientist, Amgen
Title: The Discovery of Sotorasib (AMG 510): A First-in-Class Investigational Covalent Inhibitor of KRASG12C
Date & Time: Saturday, October 21, 2023 at 11:30 – 2:30 PM
Place: Firestone Walker Barrelworks, 620 McMurray Rd, Buellton, CA 93427 (https://maps.app.goo.gl/mq4VHUfh4YmgoP8g6)
Cost: $25/$15 for students 
Note: Seating is limited. Please RSVP and submit payment here at the bottom of this page (https://docs.google.com/forms/d/e/1FAIpQLSed5A_knuSMEphett3-eAsGE3g3-FdlDbmjNzQ335yE289Ugg/viewform?usp=sf_link) 

Vu Ma has been at Amgen for over 20 years where he has worked on several discovery and pipeline projects in the medicinal chemistry department at the Thousand Oaks campus.  With a wide variety of experience in different therapeutic areas including metabolic disorders, analgesics, CNS neurology, and oncology, Vu is a valued member of the medical chemistry team.  Notably, Vu worked on the pioneering project of KRAS small molecule inhibitors. Up until 5 years ago, this ubiquitous oncogene was considered undruggable since its discovery in the 1980’s.  The CALPACS section is pleased to have Vu take us through the journey of the discovery of Sotorasib, an FDA approved treatment of non-small cell lung carcinoma.  This discovery had a big impact in the field of medicinal chemistry and this work was recognized as the Best Pharmaceutical Agent in 2022 with the Prix Galien Award.  Before Amgen, Vu worked at Pharmacopiea in combinatorial chemistry and graduated from Lehigh University with a masters degree in chemistry.

Industry Tour: San Luis Obispo Water Treatment Plant and The Water Resource Recovery Facility

Sustainability in water use is one of our state’s great challenges. Please join CALPACS for an afternoon adventure demonstrating how chemistry and engineering can address that challenge.
We will tour the Water Treatment Plant (WTP) and the Water Resource Recovery Facility (WRRF). The WTP uses ozone disinfection, ballasted flocculation, and chemical treatment to provide up to 16 million gallons of fresh water daily to the city of San Luis Obispo. The WRRF treats 4.5 million gallons of wastewater daily for discharge into San Luis Creek and for re-use in irrigation. In addition, the facility produces electricity from biogas and compost. A casual lunch will be provided at the beginning of the tour.
Please use this form to reserve your spot, as attendance is capped for safety reasons at 25 attendees.
Date: Thursday, May 4, 2023
Itinerary:
12: 15 Check-in at the WTP
1:00 Tour of WTP
2:00 Drive to WRRF
2:30 Tour of WRRF
3:30 End of Event

The WTP is on Stenner Creek Road, 0.8 miles north of Highway 1. The location is shown on this map. The WRRF is located on Prado Road, as shown here.

Cost: Free! This event is sponsored by Calpacs.